Traditional Naturopath Podcast #39

The Traditional Naturopath Podcast – 39 – (11/24/07)
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Show Notes:
Vitamin C and cancer, more info on turmeric, an herbal tonic for the adrenal glands. Dr. Bill was a guest on a NC natural health TV show!

Click the link below to watch Dr. Bill on the “Remedy This… Naturally’ TV show via streaming video!
Remedy This TV Show Link

Vitamin C and Cancer

Many years ago, Dr. Linus Pauling pioneered what he called “Orthomolecular” treatment via large doses (mega-doses) of Vitamin C for cancer with promising results… now, some research shows that this approach may have merit, and why.

A New Understanding of The Effect Of Vitamin C on Cancer Cells

“More than thirty years ago Linus Pauling and coworkers pioneered the therapeutic use of high doses of vitamin C (ascorbate) on terminal cancer patients, with promising results. Attempts by mainstream medicine to confirm Pauling’s results failed, largely because patients were given vitamin C orally, whereas Pauling’s group had gone the intravenous route. Intravenous administration achieves ascorbate concentrations that are orders of magnitude higher. Neglected by mainstream medicine, intravenous vitamin C cancer treatment continued as an alternative medical practice, although the establishment of the U.S. National Cancer Institute Best Case Series prompted a recent report of three well-documented case studies of successful vitamin C cancer therapy(1). There was another reason for the mainstream’s skepticism – the proposed mechanism of action of ascorbate appeared questionable. It was assumed that the antioxidant simply protected DNA from free radical damage, but this should protect the genetic material of healthy and cancerous tissues alike. The idea that ensuring DNA integrity should selectively favor healthy tissue over tumors seemed implausible. Indeed, this interpretation turned out to be wrong. A group at Johns Hopkins Medical School reported recently that antioxidants inhibited three tumorigenic models in vivo, but that ‘[inhibition of a human B lymphoma model was] unassociated with genomic instability but was linked to diminished hypoxia-inducible factor (HIF) levels…'(2). What the researchers found was that the differential effect of ascorbate on healthy tissue and cancer cells had nothing to do with the protection of DNA. Instead, ascorbate influenced the HIF-promoted transcription of selected genes. It was the suppression of the transcription of these genes by ascorbate that affected tumors and healthy tissues differently.

What is hypoxia-inducible factor (HIF)?

Hypoxia-inducible factor regulates the transcription of genes involved in angiogenesis, glucose uptake and metabolism, as well as other cellular functions. HIF is a protein that occurs in all mammalian cell types and that is activated when oxygen levels fall(3). Normal oxygen levels deactivate HIF by hydroxylating key proline and asparagine residues. These hydroxylation reactions are catalyzed by enzymes containing divalent iron at the active site, and require molecular oxygen. Ascorbate is needed to keep iron in the ferrous (divalent) state for these HIF-deactivating enzymes to function properly. HIF deactivation in turn prevents or slows gene transcription of proteins promoting angiogenesis and glucose metabolism(3) A growing tumor, unlike healthy tissue, needs new blood vessels (angiogenesis) to ensure a continuous supply of nutrients. And it had been known that HIF is often activated in solid tumors(3). Suppression of angiogenesis by deactivating hypoxia-inducible factor therefore selectively disadvantages tumor cells.”

An Herbal Tonic Recipe to Help the Adrenal Gland

Check out this herbal tonic for Adrenal health!

Herbal Tonic for Energy, Shingles, Herpes and More

“The adrenal glands often become ‘depleted’ as a result of the constant demands placed upon them. They are the ‘fight or flight’ glands that can become exhausted by too much stress. An individual with adrenal exhaustion will usually suffer from chronic fatigue, may complain of feeling anxiety-ridden, and will, more often than not, have a reduced resistance to allergies and infection. The adrenal glands secrete several important hormones that help maintain the balance of many body functions. Stress of any kind, fasting, temperature changes, allergies, infections, drugs, and exercise all stimulate the adrenals to release their hormones. When the adrenals release too few or too many hormones, the body responds differently to the everyday stresses of life. The adrenal cortex is involved in the production of such as cortisol, aldosterone, and androgens such as DHEA. My Adrena Tonic was formulated to support mild to moderate adrenal deficiency that can cause havoc on the immune-system and energy levels. This tonic also supports ‘Shingles, Herpes and Epstein Barr’ recovery along with Prostate Cancer Prevention.”

Go to the link above for the full “recipe” for the tonic.