Popular Diabetes Drug May Not Work, and May Be Harmful!
A recent study suggests that the diabetes drug marketed as “Actos” has no benefits, and may cause serious problems!
“A recent study notes the diabetes drug pioglitazone (Actos) has no clear-cut benefit for patients with type 2 diabetes, and may even be harmful to users. The scientists analyzed data from 22 clinical trials involving 6,200 patients who were prescribed pioglitazone — a member of the thiazolidinediones class of drugs, which theoretically increase the body’s natural insulin supply — for type 2 diabetes. The authors reported no evidence that the drug had a positive impact on patients, but they did note an increase in edema and heart failure among pioglitazone users. ‘The kernel from this review is that pioglitazone is effective in glucose-lowering, has some other beneficial and potentially harmful associated features, and just has not been evaluated in the right way to prove that it will help people lead longer and more productive lives,’ said Dr. John Buse, director of the Diabetes Care Center at the University of North Carolina School of Medicine in Chapel Hill. ‘This is true for essentially every drug available for the treatment of diabetes. I am fairly certain that we are better off with pioglitazone than without it.’ Buse said that, while the report’s findings are not incorrect, more data would be required to truly assess the drug. The report recommended that pioglitazone only be prescribed to patients showing real benefit from the therapy.”